A citizen science project to explore the human genome

Juega Genigma

As part of the ORION Open Science project, we have developed a game for smartphones to explore genomic alterations in cancer cells. We want to involve citizens in the construction of genomic reference maps that will allow us to understand which parts of the human genome play a key role in the establishment and development of cancer.

Between 2019 and 2021, more than 500 people collaborated in the co-creation and testing phases of the game. The app officially opened to the public in January 2022 with the #GenigmaChallenge for breast cancer research. More information on how it was closed can be found on the game’s official website.

Genigma Game

Next event

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29 September, 2022

The app will be closed from October 3. Data analysis begins.

After these last tests and almost 700,000 data collected, we conclude today the first #GenigmaChallenge dedicated to breast cancer. Now it is time for the scientific teams to analyse the results of GENIGMA in depth, before launching a new challenge to the public. The CNAG and the CRG would like to thank all the people […]



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The personal data you provide to the CRG upon registering your interest in Genigma project will be processed for the purpose of allowing your participation in the project and of informing you of relevant upcoming events organised in the context of the project.

Legal entity responsible for processing your data: Fundació Centre de Regulació Genòmica (CRG). Purpose of the data processing: Carrying out the management of Genigma project and, in case of giving your express consent, the submission of information of new events organized in the context of the project. Legitimation: Your own consent.Recipient: Third parties with whom CRG is legally obliged to provide the data, including sponsors of the events.Rights: You can exercise your rights of access, rectification or erasure, as well as other rights, according to our Privacy Policy. The CRG data protection officer can be contacted by email at

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Genigma Equipo
Project team: Marco Di Stefano, Elisabetta Broglio, Juan Rodríguez e Adriano Bonforti.